Research Articles
Optimized CTAB DNA Extraction for Plant Tissues: A Complete Protocol Guide for Biomedical Research
This comprehensive guide details the CTAB (Cetyltrimethylammonium bromide) method for extracting high-quality, high-molecular-weight DNA from diverse and challenging plant tissues, a critical prerequisite for downstream applications in molecular biology, genomics,...
CRISPR-Cas13: The Programmable RNA Editing Toolkit Revolutionizing Therapeutic Development
This article provides a comprehensive overview of CRISPR-Cas13 systems for targeted RNA manipulation, tailored for research scientists and drug development professionals.
From Lab to Clinic: Harnessing CRISPR-Cas Systems for Sensitive and Specific Nucleic Acid Biomarker Detection
This article provides a comprehensive overview of CRISPR-Cas systems repurposed for nucleic acid biomarker detection, targeting researchers and drug development professionals.
CRISPR vs RNAi: A Comparative Analysis of Off-Target Effects and Clinical Implications
This article provides a comprehensive comparative analysis of off-target effects (OTEs) for CRISPR-based genome editing and RNA interference (RNAi) technologies, targeting researchers and drug development professionals.
A Comprehensive Guide to CRISPR Validation Using RNA-Seq: From Basics to Advanced Analysis
This article provides a complete framework for researchers and drug development professionals to validate CRISPR-Cas9 gene editing experiments using RNA-sequencing data.
CRISPR Screening for Functional lncRNA Discovery: A Comprehensive Guide for Researchers
Long non-coding RNAs (lncRNAs) represent a vast, functionally enigmatic component of the genome with immense therapeutic potential.
CRISPR Optimization in Primary Cells: A Comprehensive Guide for Researchers and Drug Developers
This article provides a detailed guide for researchers and drug development professionals on optimizing CRISPR-Cas genome editing in primary cells.
CRISPR Biosensors vs LAMP vs RPA: A Comprehensive Guide to Amplification Efficiency for Diagnostic Development
This article provides a detailed comparison of CRISPR-based biosensors, Loop-Mediated Isothermal Amplification (LAMP), and Recombinase Polymerase Amplification (RPA) for researchers and diagnostic developers.
CRISPR Biosensing vs NGS for Mutation Detection: A 2024 Guide for Precision Medicine
This article provides a comprehensive, up-to-date comparison of CRISPR-based biosensing and Next-Generation Sequencing (NGS) for mutation detection in biomedical research and drug development.
CRISPR-Cas12a vs qPCR: A Comprehensive Sensitivity Analysis for SARS-CoV-2 Detection in Research & Diagnostics
This article provides a detailed, evidence-based comparison of CRISPR-Cas12a-based assays and quantitative polymerase chain reaction (qPCR) for detecting SARS-CoV-2, targeting researchers and diagnostic developers.